An anti-psychotic drug could treat cancer by neutralising the tumour's growth. Scientists from Cancer Research UK and McMaster University in Ontario have found that an anti-psychotic drug called thioridazine has the capability to cure cancer. The drug transforms cancer stem cells into non-cancerous cells, they have found.
Many researchers believe that cancer stem cells are the source of new cancer cells within a tumour. They claim that these cancer stem cells were resistant to current treatments, which explains why some cancers are so difficult to cure.
To find a cure for cancer stem cells, scientists had used pioneering robotics to test more than a dozen different compounds to identify a drug which could cure or eradicate the cancer stem cells. They found that the anti-psychotic drug does not eradicate the cancer stem cells but converts the cancer stem cells into non cancerous cells, that too, without damaging healthy cells.
"The unusual aspect of our finding is the way this human-ready drug actually kills cancer stem cells by changing them into cells that are non-cancerous," said Dr Mick Bhatia, scientific director at the McMaster's Stem Cell and Cancer Research Institute.
"Now we can test thousands of compounds, eventually defining a candidate drug that has little effect on normal stem cells but kills the cells that start the tumour," he added.
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Researchers are planning a clinical trial of thioridazine in combination with standard anti-cancer drugs for adults with acute myeloid leukaemia.
"It's too early to say whether thioridazine could be used to treat cancer patients, but the research opens up some interesting questions for further investigation. Use of thioridazine at dose levels required to treat cancer may well result in significant side effects that limit or prohibit its use. Further research will be needed before we can be sure," said Dr Tim Somervaille, researcher at Cancer Research UK, in a statement.
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Daniel Haszard comment-Thioridazine is in the class of 'typical' antipsychotics called phenothiazines of which 'Thorazine' is best known.This group is 50 years old and I have been taking Thorazine for 2 years for my PTSD to help me sleep.Continued research may show that it is the whole class of phenothiazines that have anti-cancer properties.
{"..researchers believe it will be safer for cancer patients because they’re only on it for eight to 21 days instead of a number of years, and they take half the dose..."
"..McMaster has since discovered schizophrenia patients who took the drug had 10 times fewer instances of cancer..."}
A cancer suppressive side effect of antipsychotic drugs would be a wonderful blessing.
A patient speaks:
There are two kinds of antipsychotics the 50 year old tried and tested inexpensive *typical* antipsychotics like Thorazine,and the newer so-called *atypicals* like Risperdal,Seroquel,Zyprexa.
These drugs are lifesavers for those with delusional mental illness which is only 1 percent of the population.
The saga of the so called *atypical antipsychotics* is one of incredible profit.Eli Lilly made $65 BILLION on Zyprexa franchise (*Viva Zyprexa* Lilly sales rep slogan).
Described as *the most successful drug in the history of neuroscience* the drugs at $12 pill are used by states to medicate deinstitutionalized mental patients to keep them out of the $500-$1,200 day hospitals.There is a whole underclass block of our society,including children in foster care that are the market for these drugs,but have little voice of protest if harmed by them.I am an exception,I got diabetes from Zyprexa as an off-label treatment for PTSD and I am not a mentally challenged victim so I post.
Google-Haszard Zyprexa
--Daniel Haszard - FMI http://www.zyprexa-victims.com
Posted by: Jehovahinfo | 05/27/2012 at 06:24 AM